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Water and a protic ionic liquid acted as refolding additives for chemically denatured enzymes

TitleWater and a protic ionic liquid acted as refolding additives for chemically denatured enzymes
Publication TypeJournal Article
Year of Publication2012
AuthorsAttri, P, Venkatesu, P, Kumar, A
JournalOrganic & Biomolecular Chemistry
Volume10
Issue37
Pagination7475-7478
Date PublishedJUN
Type of ArticleArticle
ISSN1477-0520
Abstract

In this communication, we present the ability of water and a protic ionic liquid, triethyl ammonium phosphate (TEAP) to act as refolding additives for the urea-induced chemical denaturated state of the two enzymes, alpha-chymotrypsin and succinylated Con A. We show that the enzymatic activity is regained and in certain circumstances enhanced.

DOI10.1039/c2ob26001h
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.568

Divison category: 
Physical and Materials Chemistry