Residue dependent hydrogen-bonding preferences in orthanilic acid-based short peptide beta-turn motifs
|Title||Residue dependent hydrogen-bonding preferences in orthanilic acid-based short peptide beta-turn motifs|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||Jedhe, GS, Vijayadas, KN, Kotmale, AS, Sangtani, E, Shinde, DR, Gonnade, RG, Rajamohanan, PR, Sanjayan, GJ|
This communication describes the competition between native beta-turn (C10) and 2-aminobenzenesulfonic acid (SAnt)( orthanilic acid)-based pseudo beta-turn (C11) in their hybrid peptides. Solid-state crystal structure and solution-state NMR studies revealed that C10 and C11 can be simultaneously observed under appropriate conditions. The variable temperature NMR coefficient data suggest that the isolated C11/C14 hydrogen bond is weaker in comparison with the consecutive C10 and C11 turns.
|Type of Journal (Indian or Foreign)|| |
|Impact Factor (IF)|| |