Recent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon-carbon bond-forming reactions

TitleRecent advances in employing homoenolates generated by N-heterocyclic carbene (NHC) catalysis in carbon-carbon bond-forming reactions
Publication TypeJournal Article
Year of Publication2015
AuthorsMenon, RS, Biju, AT, Nair, V
JournalChemical Society Reviews
Volume44
Issue15
Pagination5040-5052
Date PublishedMAY
ISSN0306-0012
Abstract

The use of NHCs for generating homoenolate species has gained widespread popularity in recent years. A number of highly stereoselective processes of NHC-homoenolates have emerged. Homoenolate reactions have also been employed as key steps in the total synthesis of a number of natural products. The use of compatible co-catalysts, improved NHC-catalyst design and the use of novel precursors for homoenolate generation are among the major developments in this area that were disclosed recently. This tutorial review organises and presents the advancements in this rapidly growing area of catalysis and in the process updates a previous account published in 2011 in this journal.

DOI10.1039/c5cs00162e
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

34.09

Divison category: 
Organic Chemistry