Potassium phosphate or silica sulfuric acid catalyzed conjugate addition of thiols to alpha,beta-unsaturated ketones at room temperature under solvent-free conditions

TitlePotassium phosphate or silica sulfuric acid catalyzed conjugate addition of thiols to alpha,beta-unsaturated ketones at room temperature under solvent-free conditions
Publication TypeJournal Article
Year of Publication2006
AuthorsPore, DM, Soudagar, MS, Desai, UV, Thopate, TS, Wadagaonkar, PP
JournalTetrahedron Letters
Volume47
Issue52
Pagination9325-9328
Date PublishedDEC
Type of ArticleArticle
ISSN0040-4039
Keywordsalpha, beta-unsaturated ketones, chalcones, conjugated enones, Michael addition, Potassium phosphate, silica sulfuric acid, thiols
Abstract

Potassium phosphate and silica sulfuric acid have been found to be useful and highly efficient catalysts for conjugate addition of thiols to alpha,beta-unsaturated ketones under solvent-free conditions, at room temperature. Silica sulfuric acid (SSA) was found to be suitable for electron-deficient enones while potassium phosphate was found to effect thia-Michael addition with both, electron-deficient as well as electron-rich conjugated ketones. (c) 2006 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetlet.2006.10.114
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

2.347

Divison category: 
Polymer Science & Engineering