Ortho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox relay catalysis

TitleOrtho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox relay catalysis
Publication TypeJournal Article
Year of Publication2019
AuthorsSancheti, SP, Akram, MO, Roy, R, Bedi, V, Kundu, S, Patil, NT
JournalChemistry-An Asian Journal
Date PublishedOCT
Type of ArticleArticle; Early Access
ISSN1861-4728
Keywordsbinary catalyst system, Gold catalysis, organocatalyst, photoredox, synthetic methodology
Abstract

Reported herein is an ortho-oxygenative 1,2-difunctionalization of diarylalkynes under merged gold/organophotoredox catalysis to access highly functionalized 2-(2-hydroxyaryl)-2-alkoxy-1-arylethan-1-ones. Detailed mechanistic studies suggested a relay process, initiating with gold-catalyzed hydroalkoxylation of alkynes, to generate enol-ether followed by a key formal [4+2]-cycloaddition reaction. The successful application of the present methodology was also shown for the synthesis of benzofurans.

DOI10.1002/asia.201901275
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.698

Divison category: 
Organic Chemistry