One-pot synthesis of 2,4,5-trisubstituted imidazoles using MoO3/SiO2, an efficient and recyclable catalyst

TitleOne-pot synthesis of 2,4,5-trisubstituted imidazoles using MoO3/SiO2, an efficient and recyclable catalyst
Publication TypeJournal Article
Year of Publication2011
AuthorsBhosale, SV, Kalyankar, MB, Nalage, SV, Bhosale, DS, Pandhare, SL, Kotbagi, TV, Umbarkar, SB, Dongare, MK
JournalSynthetic Communications
Volume41
Issue5
PaginationPII 932996516
Date PublishedJAN
ISSN0039-7911
Keywordsbenzil, benzoin, cyclocondensation, imidazoles, MoO3, One-pot, SiO2, solid acid
Abstract

[image omitted] A simple one-pot synthesis has been developed for the synthesis of 2,4,5-trisubstituted imidazoles using an efficient and recyclable MoO3/SiO2 solid acid catalyst by condensation of benzil or benzoin, benzaldehyde, and ammonium acetate in acetonitrile as a solvent. Using this solid catalyst, the reactions could be carried out under mild reaction conditions with very good yield of imidazoles, up to 95%. This catalyst could be recycled very easily, which makes this methodology environmentally benign.

DOI10.1080/00397911003644415
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

1.24

Divison category: 
Catalysis and Inorganic Chemistry
Organic Chemistry