Gold(I)-catalyzed hydroxy group assisted C(sp(2))-H alkylation of enaminones with diazo compounds to access 3-alkyl chromones

TitleGold(I)-catalyzed hydroxy group assisted C(sp(2))-H alkylation of enaminones with diazo compounds to access 3-alkyl chromones
Publication TypeJournal Article
Year of Publication2019
AuthorsBagle, PN, Mane, MV, Sancheti, SP, Gade, AB, Shaikh, SR, Baik, M-H, Patil, NT
JournalOrganic Letters
Volume21
Issue1
Pagination335-339
Date PublishedJAN
Type of ArticleArticle
ISSN1523-7060
Abstract

A strategy for expedient synthesis of 3-substituted chromones from easily available o-hydroxyarylenaminones and diazo compounds has been developed. Carefully conducted experimental and computational studies led us to propose an uncommon mechanistic pathway involving the hydroxyl group assisted alkylation of enaminones with in situ generated gold carbenes.

DOI10.1021/acs.orglett.8b03989
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

6.492

Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry