Expeditious assembly of 3,4-benzannulated 8-oxabicyclo[3.2.1]octane systems by [2+2+2] alkyne cyclotrimerisation: Total synthesis of (-)-bruguierol A

TitleExpeditious assembly of 3,4-benzannulated 8-oxabicyclo[3.2.1]octane systems by [2+2+2] alkyne cyclotrimerisation: Total synthesis of (-)-bruguierol A
Publication TypeJournal Article
Year of Publication2007
AuthorsRamana, CV, Salian, SR, Gonnade, RG
JournalEuropean Journal of Organic Chemistry
Issue33
Pagination5483-5486
Date PublishedNOV
Type of ArticleArticle
ISSN1434-193X
Keywordscyclotrimerisation, epoxidation, Total synthesis, Wilkinson's catalyst
Abstract

Facile construction of benzene-fused 8-oxabicyclo[3.2.1]octane systems by employing a cross alkyne cyclotrimerisation reaction was explored. With this procedure, (-)-bruguierol A was synthesised, and its absolute configuration was established.

DOI10.1002/ejoc.200700648
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.068

Divison category: 
Organic Chemistry
Physical and Materials Chemistry