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Asymmetric total synthesis of eicosanoid

TitleAsymmetric total synthesis of eicosanoid
Publication TypeJournal Article
Year of Publication2005
AuthorsMohapatra, DK, Yellol, GS
JournalArkivoc
IssuePart 3
Pagination144-155
Date PublishedJAN
Type of ArticleArticle
Keywordscyclopropanation, eicosanoid, lipoxygenase inhibitors, Ring-closing metathesis, Stereoselective
AbstractAn asymmetric total synthesis of eicosanoid 4 starting from 2,2- dimethyl-( R)- 1,3- dioxolane-4- carbaldehyde is described. The key steps involved for the synthesis include modified Simmons-Smith cyclopropanation, stereoselective reduction, ring-closing metathesis (RCM) and Nozaki- Hiyama- Kishi coupling reaction.
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)1.177
Divison category: 
Organic Chemistry