Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes

TitleAsymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes
Publication TypeJournal Article
Year of Publication2013
AuthorsYetra, SReddy, Kaicharla, T, Kunte, SS, Gonnade, RG, Biju, AT
JournalOrganic Letters
Volume15
Issue20
Pagination5202-5205
Date PublishedOCT
ISSN1523-7060
Abstract

N-Heterocyclic carbene (NHC)-catalyzed highly enantioselective lactonization of modified enals with enolizable aldehydes, proceeding via the alpha,beta-unsaturated acylazolium intermediates, is reported. The reaction results in the asymmetric synthesis of synthetically important 4,5-disubstituted dihydropyranones.

DOI10.1021/ol4026155
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

6.324

Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry