Assessing the role of FecB mutation in productivity of Indian sheep

TitleAssessing the role of FecB mutation in productivity of Indian sheep
Publication TypeJournal Article
Year of Publication2005
AuthorsPardeshi, VC, Sainani, MN, Maddox, JF, Ghalsasi, PM, Nimbkar, C, Gupta, VS
JournalCurrent Science
Date PublishedSEP
Type of ArticleArticle
KeywordsFecB (Booroola) gene, Garole sheep, PCR-RFLP test, prolificacy

DNA samples from four Indian sheep breeds, viz. Garole, Deccani, Bannur and Madras Red were screened by PCR-RFLP to determine the presence of FecB mutation in these breeds. The Garole was the only breed, which carried the FecB mutation. The FecB mutation was introgressed from Garole sheep into Deccani sheep and Bannur sheep, and the performance of the crossbred sheep is being monitored in subsequent generations. Approximately half of the first backcross ewes (progeny of FecB heterozygote F1 rams) was found to carry one copy of FecB mutation, as expected. The FecB PCR-RFLP test was found to be fast, accurate and useful as a tool for making breeding decisions.

Type of Journal (Indian or Foreign)


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Divison category: 
Biochemical Sciences