Aryne [2,3] stevens rearrangement
|Title||Aryne [2,3] stevens rearrangement|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||Roy, T, Thangaraj, M, Kaicharla, T, Kamath, RV, Gonnade, RG, Biju, AT|
Arynes are employed in the transition-metal-free and mild [2,3] Stevens rearrangement of tertiary allylic amines for the synthesis of functionalized homoallylic amines in moderate to good yield with a broad substrate scope. The key nitrogen ylide intermediate was generated by the N-arylation of allyl amines using arynes. Moreover, the reaction of chiral allyl amines with arynes resulted in the enantiospecific synthesis of homoallylic amines. In addition, preliminary studies on the [1,2] Stevens rearrangement is also presented.
|Type of Journal (Indian or Foreign)|| |
|Impact Factor (IF)|| |