Alum: an efficient catalyst for one-pot synthesis of alpha-aminophosphonates

TitleAlum: an efficient catalyst for one-pot synthesis of alpha-aminophosphonates
Publication TypeJournal Article
Year of Publication2009
AuthorsSonar, SS, Shelke, KF, Kakade, GK, Shingate, BB, Shingare, MS
JournalChinese Chemical Letters
Volume20
Issue9
Pagination1042-1046
Date PublishedSEP
ISSN1001-8417
KeywordsAldehyde/ketone, alpha-Aminophosphonates, Alum, Amine, Solvent-free, Triethyl phosphite
Abstract

Alum (KAl(SO(4))(2)center dot 12H(2)O) is an inexpensive, efficient, non-toxic and mild catalyst for the one-pot synthesis of alpha-aminophosphonates. A three component reaction of an aldehyde/ketone, an an-tine and triethyl phosphite was carried out under solvent-free conditions to afford the corresponding alpha-aminophosphonates in short reaction times and high yields with the green aspects by avoiding toxic catalysts and solvents. (C) 2009 Murlidhar S. Shingare. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

DOI10.1016/j.cclet.2009.04.024
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

0.775

Divison category: 
Organic Chemistry