AgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols
|Title||AgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols|
|Publication Type||Journal Article|
|Year of Publication||2017|
|Authors||Kaicharla, T, Jacob, A, Gonnade, RG, Biju, AT|
The reaction of 2-naphthols with aziridines in the presence of AgOTf resulting in a dehydrative, formal [3+2] annulation is reported. The reaction allows the synthesis of functionalized benzoindolines, and tolerates a broad range of functional groups. A preliminary study on themechanism of this reaction indicates an SN1-type ring-opening of aziridines. This method is demonstrated for the one-pot synthesis of benzoindoles.
|Type of Journal (Indian or Foreign)|| |
|Impact Factor (IF)|| |