AgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols

TitleAgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols
Publication TypeJournal Article
Year of Publication2017
AuthorsKaicharla, T, Jacob, A, Gonnade, RG, Biju, AT
JournalChemical Communications
Volume53
Issue58
Pagination8219-8222
Date PublishedJUL
Abstract

The reaction of 2-naphthols with aziridines in the presence of AgOTf resulting in a dehydrative, formal [3+2] annulation is reported. The reaction allows the synthesis of functionalized benzoindolines, and tolerates a broad range of functional groups. A preliminary study on themechanism of this reaction indicates an SN1-type ring-opening of aziridines. This method is demonstrated for the one-pot synthesis of benzoindoles.

DOI10.1039/c7cc03425c
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

6.567

Divison category: 
Center for Material Characterization (CMC)
Organic Chemistry