AgNO3-Catalysed intramolecular cyclization: access to functionalized cyclopentanones and spiro-cyclopentanones

TitleAgNO3-Catalysed intramolecular cyclization: access to functionalized cyclopentanones and spiro-cyclopentanones
Publication TypeJournal Article
Year of Publication2019
AuthorsBhoite, SP, Bansode, AH, Burate, PA, Suryayanshi, G
JournalAsian Journal of Organic Chemistry
Date PublishedAUG
Type of ArticleArticle
Abstract

An efficient AgNO3-catalysed method has been developed for the synthesis of functionalized cyclopentanones and spiro-cyclopentanones through intramolecular cyclization between ynones and cyanoacrylate/aryl/alkylidene malononitrile using DBU as a base. Easy availability of starting materials and mild reaction conditions makes this protocol more feasible over previously reported methods. The functionalized cyclopentanones and spiro-cyclopentanones were synthesized in good to excellent yields with a broad substrate scope.

DOI10.1002/ajoc.201900453
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

2.496

Divison category: 
Chemical Engineering & Process Development